Substances authorised in Europe
Updated on 15/10/2026
Official sources automatically checked on 20/10/2026.
Which substances can be freely used to make your own herbal preparation in Europe? This page lists the basic substances approved by the European Union, French “natural preparations of low concern” (PNPP), their equivalents in other countries, substances currently under review or rejected, and links to the recipes in this collection. This document was updated on October 13, 2026; it is not a substitute for legal advice.
List as of October 13, 2026 (Part C of the Annex to Implementing Regulation (EU) No. 540/2011). Approvals are not time-limited. Specific uses, doses, and crops are listed in the review report for each substance (EU Pesticide Database).
| Substance | Scientific/Chemical Name | Approval Regulations | Uses Approved by Regulation (Summary) | Organic Farming |
|---|---|---|---|---|
| Field horsetail | Field horsetail | Regulation (EU) No. 462/2014 | Downy Mildew and Powdery Mildew: Vineyards, Orchards, and Vegetable Farms | Yes |
| Chitosan hydrochloride | Chitosan hydrochloride | Regulation (EU) No. 563/2014 | Boosting Natural Defenses: Grains, Vines, and Vegetable Crops | Yes |
| Sucrose | Sucrose | Regulation (EU) No. 916/2014 | Boosting natural defenses; grapevines (downy mildew, flavescence dorée leafhopper) | Yes |
| Calcium hydroxide | Ca(OH)₂ | Regulation (EU) 2015/762 | Canker (Nectria galligena) on Fruit Trees | Yes |
| Vinegar | Acetic acid ≤ 10% | Regulation (EU) 2015/1108 | Disinfection of tools and seeds; weed control | Yes |
| Lecithins | Lecithins (E322) | Regulation (EU) 2015/1116 | Powdery Mildew: Vineyards, Fruit Tree Cultivation, Vegetable Farming | Yes |
| Willow bark | Salix spp. bark | Regulation (EU) 2015/1107 | Downy mildew and powdery mildew: grapevines, apple trees, peach trees | Yes |
| Fructose | Fructose | Regulation (EU) 2015/1392 | Boosting natural defenses; grapevines (downy mildew, leafhoppers) | Yes |
| Sodium hydrogen carbonate | NaHCO₃ | Regulation (EU) 2015/2069 (to be confirmed) | Powdery Mildew: Vineyards, Fruit Tree Cultivation, Vegetable Farming | Yes |
| Whey | Whey | Regulation (EU) 2016/560 | Powdery mildew; tool disinfection | Yes |
| Diammonium phosphate | (NH₄)₂HPO₄ | Regulation (EU) 2016/548 | Bait in traps (fruit flies) | Yes (traps) |
| Sunflower oil | Sunflower oil | Regulation (EU) 2016/1978 | Powdery Mildew on Tomatoes | Yes |
| Clay coal | Charcoal + bentonite | Regulation (EU) 2017/428 | Vines: Esca | No |
| Stinging Nettle | Urtica spp. | Regulation (EU) 2017/419 | Insects, mites, and fungi: vineyards, vegetable farming, and fruit tree cultivation (according to the review report) | Yes |
| Hydrogen peroxide | H₂O₂ | Regulation (EU) 2017/409 | Disinfection of Tools and Surfaces | Yes |
| Sodium chloride | NaCl (food grade) | Regulation (EU) 2017/1529 | Vineyards (limited use, 6 kg/ha/year); mushroom farms | Yes |
| Beer | Beer | Regulation (EU) 2017/2090 | Slug and Snail Traps | Yes |
| Mustard Seed Powder | Mustard Seed Powder | Regulation (EU) 2017/2066 | Wheat Seed Treatment (Rotten Seeds) | Yes |
| Talc E553b | Hydrated magnesium silicate | Regulation (EU) 2018/691 | Physical barriers (pear psyllid, sunscald); under review | Yes |
| Onion oil | Allium cepa oil | Regulation (EU) 2018/1295 | Repellent (carrot fly), dispensers | Yes |
| L-cysteine | L-cysteine (E920) | Regulation (EU) 2020/642 | Exact usage to be confirmed | Yes |
| Cow's milk | Cow's milk | Regulation (EU) 2020/1004 | Powdery mildew (vegetable crops), to be confirmed | Yes |
| Onion bulb extract | Allium cepa L. bulb extract | Regulation (EU) 2021/81 | Vegetable farming and arboriculture (uses to be confirmed) | Yes |
| Chitosan | Chitosan (≥ 85%) | Regulation (EU) 2022/456 | Boosting Natural Defenses: Vines, Grains, and Vegetable Crops | To be confirmed |
| Magnesium hydroxide | Mg(OH)₂, E528 | Regulation (EU) 2024/836 | Grapevine: downy mildew, powdery mildew, black rot (≤ 3.5 kg/ha, 1 application per year) | No |
| Sainfoin (pellets) | Onobrychis viciifolia | Regulation (EU) 2024/1768 | Grapevine: Xiphinema index nematode | No |
| Processed scallions | Allium fistulosum L. | Regulation (EU) 2024/2878 | Usage to be confirmed | To be confirmed |
| Grape Seed Extract | Vitis vinifera L. seed extract | Regulation (EU) 2025/96 | Downy mildew of grapevines; apple trees, lettuce, potatoes | To be confirmed |
In organic farming, Annex I of Implementing Regulation (EU) 2021/1165 permits the specifically listed basic substances and, more generally, those that are foodstuffs of plant or animal origin.
| Substance | Subject | What is the current status of the case? |
|---|---|---|
| Water | Approval as a base substance | Consultation with Member States (October 2025) |
| Sodium hypochlorite (< 1%) | Seed Treatment | No qualified majority (December 2025); issue put on hold |
| Ethyl formate | Post-harvest fumigation | Application filed (March 2025) |
| Ozone | Approval | Discussion (May 2025), Member States divided |
| Potassium sorbate | Use against nematodes | New Application (July 2025) |
| Horsetail | Post-harvest extension | Filed (March 2025) |
| Chitosan hydrochloride | Application: rapeseed, grapevines, turf | EFSA Reports (June 2026) |
| Sodium chloride | Extension: Ragweed Weed Control (roads, railways) | Scheduled vote (September 2026) |
| Talc E553b | Review of Approval | Risk of withdrawal (proposed carcinogen classification) |
Source: Minutes of the European Commission’s Standing Committee (SCoPAFF, Plant Protection Products Section), March 2025 through September 2026. A simplification proposal (“omnibus,” COM(2025) 1030) calls for the rewriting of Article 23.
| Substance | Decision |
|---|---|
| Chili Pepper Oleoresin (Capsicum) | Vote in favor of rejection (May 2026) |
| Quassia amara wood extract | Proposed Non-Approval (2026) |
| Yeast-Fermented Stinging Nettle (New Recipe) | Rejection of the extension put to a vote (September 2026) |
| Burdock (Arctium lappa) | Rejected (RE (EU) 2015/2082) |
| Yarrow, wormwood, mugwort, comfrey, tansy, propolis, rhubarb, soapwort, savory, and oregano (essential oils), paprika, pine tar, vine shoot tannins, CO₂ | Candidates Rejected by the Commission (2022 List) |
A homemade preparation made from these substances is not covered under the basic substances program.
Article L.253-1 of the Rural Code distinguishes between two categories of PNPPs: those composed of basic substances (see the European list above) and those composed exclusively of natural substances used as biostimulants (SNUBs). SNUBs are classified as fertilizers: their labeling may only highlight their natural character and their use as biostimulants.
Permitted processes: no processing or manual, mechanical, or gravitational methods; dissolution or extraction with water or alcohol; steam distillation; heating to remove water. Examples: fermentation (liquid manure), maceration, decoction, infusion, pressing. Excluded: freeze-drying, atomization, ultrasound, microwaves.
Who is authorized as a SNUB? The list is open:
Requirements: Keep the registration form on file for 3 years; note the expiration date; do not apply within 3 days of harvest for unheated preparations; keep essential oils at least 5 m away from a water source. Plants listed in the EFSA Compendium (e.g., comfrey): document that the dose is safe.
This is a tentative grouping; the official numbered list is set forth in Article D.4211-11 of the Public Health Code.
Italy — “plant growth promoters, enhancers of plants’ natural defenses” (Ministerial Decree No. 229771 of May 20, 2022, Annex 2), 15 categories:
Choose a country or territory to see the bio-preparation recipes authorised there, with a summary of the legal framework and the official texts.
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Each recipe shows its regulatory status. Open a recipe to see the details and official texts.
This document is a summary based on official texts and institutional sources as of October 13, 2026. It does not constitute legal advice or a recommendation for use. Always check the substance review report and the regulations in your country before preparing or using the substance.